1) After hours of trying to fix the problem, she was at her wit's end.

2) Dealing with his stubborn toddler had him at his wit's end.

3) The endless delays had passengers at their wit's end.

4) Trying to meet the deadline left him at his wit's end.

5) The constant barking of the neighbor's dog left her at her wit's end.

6) Dealing with the difficult customer left the employee at her wit's end.

7) Juggling work and family responsibilities had her at her wit's end.

8) The never-ending cycle of cleaning up after her roommate had her at her wit's end.

9) Struggling to understand the complex math problem had him at his wit's end.

10) The ongoing noise complaints from the neighbors had the landlord at his wit's end.